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Provention Bio Inc (NASDAQ: PRVB) has initiated the Phase 2a PREVAIL-2 study evaluating PRV-3279 in systemic lupus erythematosus (SLE). PRV-3279 is a humanized bispecific DART molecule targeting the B-cell surface proteins CD32B & CD79B, which can intercept the pathophysiology of SLE & other B cell-mediated autoimmune diseases and prevent the immunogenicity of gene therapies.
...read full article on Benzinga